Ketamine is an anesthetic, a medication used for induction and maintenance of anesthesia. It is one of the safest anesthetics, as, in contrast with opiates, ether, and nitrous oxide, it suppresses neither respiration nor heart rate. Some anesthetics are flammable or explosive, but ketamine is relatively easy to handle safely. Ketamine is a novel chemical created in a quest for a safer anesthetic, safer than the PCP from which it is derived. Buy Ketamine Online.
Besides anesthesia, ketamine is also used for acute pain management and treatment of depression. It induces dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia.[19] The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation.[19] At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression.[20] However, the antidepressant action of a single administration of ketamine wanes with time and the effects of repeated use are largely unknown, and are an area of active investigation.
Therapeutic uses
The FDA has approved ketamine for general anesthesia only, but the drug has some off-label uses. Details are below.
Inducing general anesthesia
Doctors use ketamine to induce general anesthesia alone or with other general anesthetics, such as nitrous oxide. They use it in the emergency department setting to produce short-term sedation whenTrusted Source:
- reducing fractures
- treating joint dislocations
- repairing wounds in uncooperative individuals, such as children
Treating pain
Practitioners use low doses that do not produce dissociation to relieve severe pain from the following trusted Source conditions:
- trauma
- fractures
- abdominal pain
- arm or leg pain
- low back pain
Treating status epilepticus
Status epilepticus is when a person has a seizure that lasts longer than 5 minutes or has more than one seizure within 5 minutes.
Refractory status epilepticus (RSE) is a form of status epilepticus that does not respond to standard antiseizure drugs. It is a severe disease that can cause brain damage and death.
A 2015 study found that ketamine may effectively treat RSE. However, further research is necessary to verify the study findings and prove the safety of using ketamine to treat this condition.
Treating depression
Research in 2017 by Trusted Source notes that some studies indicate ketamine can quickly relieve depression in people who do not respond well to other treatments.
Despite these positive results, the authors warn that data on the use of ketamine for this condition are limited, so practitioners should consider the risks of the drug before prescribing it.
A 2016 study trusted Source cautions that the inappropriate use of ketamine is a worldwide health problem due to its hallucinogenic properties. With this in mind, they urge doctors to prescribe standard antidepressants before trying ketamine for depression.
Treating Anxiety
Research on the use of ketamine for anxiety is scarce. However, one study suggests that it may help people with social anxiety disorder (SAD). This condition involves a marked fear of social situations.
In the 2017 clinical trialTrusted Source tested the drug on 18 participants and concluded that it might effectively treat SAD.
Because several other trials indicate ketamine may have significant antianxiety effects, the authors encouraged future studies to explore this possible benefit more fully.
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IS KETAMINE LEGAL?
“Is Ketamine legal?” is a common, and legitimate question from those looking to explore psychedelic medicine for therapeutic treatment of their depression and anxiety.
Ketamine is legal for medical use in the United States and select countries across the world.
The use of ketamine is regulated, meaning it can only be administered or prescribed by licensed clinicians with the authority and expertise to support its effective use.
When used within the context of a surgical procedure or as prescribed by a licensed clinician, it is legal to administer. Any other use of this medicine outside of these guidelines, such as recreationally, is illegal and currently unregulated.
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